Posted 20 August 2012 - 07:32 PM
Amy - I was dx with CML in May 2010 and put on 400mg. Gleevec. My response was similar to yours but I began to suffer myelosuppression (Neutrophils went significantly below normal) and I was reduced to 300mg. Gleevec. That was a failure and my leukemic cell count started to increase again significantly back to 100% (i.e. Gleevec failure). I was put on Sprycel and once I adapted, my leukemic cell count went from 100% to 0% in seven months. And that happened on only 20mg. Sprycel. Zero side affects with Sprycel (that I can feel) at that dose.
Consider making the switch. You'll be glad you did. You can always go back if it doesn't agree with you.
Diagnosed 11 May 2011 (100% FiSH, 155% PCR)
with b2a2 BCR-ABL fusion transcript coding for the 210kDa BCR-ABL protein
Sprycel: 20 mg per day - taken at lights out with Quercetin and/or Magnesium Taurate
6-8 grams Curcumin C3 complex.
2015 PCR: < 0.01% (M.D. Anderson scale)
2016 PCR: < 0.01% (M.D. Anderson scale)
March 2017 PCR: 0.01% (M.D. Anderson scale)
June 2017 PCR: "undetected"
September 2017 PCR: "undetected"