Haven't been on here for a long time so I hope I am doing this right. Looking for all you CML gurus and your wisdom. Used to be on here quite a bit but for those who don't remember me (Trey~I hope you are still out there) here is my background. Dxd in march 07, started on Gleevec with all the fun side effects but otherwise had a good response then not so good, up the dose, good then not so good, etc. til failure in march 2010. Switched to Sprycel. Very slow but steady progress til finally PCRU last October. One hiccup but been a big "0" since december.
Ok so about the pericardial effusion. Mild, irritating cough last summer. Chest xray & echo. All good. December still cough, Onc not concerned. March this year, cough my head off when I lay down, chest starting to feel tight, Onc listens to chest and heart and says nothing. July 2, 2012 see Onc. He says he can hear me breathing from across the room, duh. Tells me about some patients now developing high blood pressure in the arteries in the lungs and sends me off for a more detailed echo. Not that but Pericardial effusion with heart function @ 60%. Puts me Furosemide. Take for 3 days then 1-2x a week as needed. First two weeks doing much better, from then on not so much til last Friday I call asking if ok that I take it more often, describe what's going on and they freak! Take it NOW! I'm told, call you right back! Calls back with appointment on Tuesday for Echo and Thursday with Cardiologist and if things get worse, don't try to get to us, (2 hours away) go to nearest ER. This was all by the on-call Onc because the clinic only does chemo on Fridays (no appointments). I pushed the echo to Tuesday so this could all be cleared by my Onc first on Monday (which it is).
My question; First, should I have been taken off Sprycel? and second, do you think tasigna will work for me after already having had a failure on Gleevec?
any input will be greatly appreciated!