Hi, Shar. . .welcome to the club!
When some people start Sprycel they have pretty severe headaches, which last for a week or two. I had to switch from Gleevec to Sprycel. I took a 5-day drug break to clear my body of any residual Gleevec, and then started taking Sprycel at half dose (50 mg) for a week. After a week, I took full dosage (100 mg). My headaches were minimal for a week, maybe a bit more, and since then I've had very few side effects, other than fatigue, which seems to be a given with cml/tki's.
As you begin taking Sprycel, your oncologist will want to monitor your blood counts. Typically, people diagnosed have a pretty high WBC, then take Hydroxyurea to bring the counts down. The TKI will also bring your counts down, so it's important to monitor your blood pretty regularly early in your diagnosis.
Despite the cml and the tki meds, I continue to have an extremely active life. I am a full time middle-school teacher. I kayak, snowboard, ride motorcycles, and generally am on the go 24/7. Hopefully you will find that you have very few side effects with your meds. Most people do pretty well with them, though not everyone.
Be prepared for a couple weeks of headaches. Check with your oncologist about over-the-counter pain meds. Sprycel is hard on the liver, so you should NOT take tylenol. My oncologist has assured me that advil or aleve is o.k. as long as it's not taken long term. I try to stay away from it as much as possible. Drugs.com is a good resource to check for drug interactions.
P.S. TKI stands for tyrosine kinase inhibitor (not sure I got the spelling correct). You can google it, or check out Trey's Blog to get a description of how the medication works.