Hi All,
I just got a call from my oncologist and wanted to see what you all thought about this. As some of you may know, I have been stalled out on Tasigna, so my oncologist wanted to try increasing my dosage from 600 mg daily to 800 mg daily. We are testing once a month, (April3rd and now May 3rd) but this time we sent out two PCR's at the same time. One to Mayo and one to Blood Center of Wisconsin, where I usually get tested. I know you cannot compare labs, but this is kind of a big difference. My log reduction at BCW went from .9 to 1.2 log reduction in a month and my test at Mayo, which is done using the international scale came back with a 1.3%, which corroborates my CCyR, which from what I understand is a 2 log reduction. At one lab, I have a 1.2 log reduction and at another lab I have a 2 log reduction. The mayo lab uses ABL as the control and the other lab uses G6PDH. I know with PCRs, you look for trends, but this still has peaked my curiosity.
