My 38 year old husband was diagnosed with CML in 2007. He started on Gleevec and but the side effects were awful so his doc switched him to Sprycel about 2 years ago. He started on 100 Mg per day but last year they dropped him down to 50 Mg per day when the meds started killing off his good cells, not just the bad. He started noticing a few months ago that his hair had started to thin (he's always had really thick hair). He still has hair but it is getting noticeably thinner. We'd like to try an OTC preventative like Rogaine. Has anyone tried this treatment and has it helped? Are there any potential adverse interactions of using Rogaine with Sprycel? We also may have to face that the hair loss may be age-related instead of drug-related but his family all had thick hair into their twilight years.
Also, my husband has serious concern that being on Sprycel has significantly decreased his muscle mass. Over the years we have noticed that his legs, arms, etc. aren't as bulky as they used to be. He has a light work-out routine and a fairly physical job but feels he is losing muscle mass. Being 38 he's naturally concerned with not just his health, but his physical appearance. If he is going to be on Sprycel or something similar for the next 20 years (God-willing!), then do we really know all of the side effects? There is very little to go on when doing web research. I'd love to hear other thoughts - if you have had similar experiences or concerns. His doctor is happy with his bloodwork numbers and doesn't want to switch meds so we are at looking for some validation to our concerns. Thanks and be well!