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Question re; chromosones. OK CML + Philadelphia chromosome is what I have. I understand there are 23 chromosome and the PH+ is the breakage and fusion of #9 & #22. My question is where do the chromosome come into play, in the whole scheme of stem c

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#1 pamsouth



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Posted 22 January 2012 - 04:38 PM

We have the bone marrow that make the stem cell, that makes all the blood.  Somewhere at the top of the chain, we have the Leukemia stem cell.  For CML + PH it is on the Myeloid side, that makes the red cells, platelets, white cell.  And these particular white cells are make up of granulocytes, which are the Neutrophils, Basophils, Eosinophils. Is that right so far?   So Where do the chromosomes come into play, what part of this diagram or equation do the chromosomes fit into all of this?



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